chapter 1 the programmable web and its inhabitants
Chapter 1 - The role and environment of managerial finance
... governance, the role of ethics and the agency issue Understand the financial institutions and markets and the role they play in managerial finance Discuss business taxes and their importance in ... Finance and Business Finance: the art and science of managing money Two broad areas: – Financial Services: the design and delivery of advice and financial products to individuals, business and ... Managerial Finance / 6th edition Financial Institutions and Markets Financial Markets: – Forums in which suppliers of funds and demanders of loans and investments can transact directly – Two main...
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Tài liệu Báo cáo khoa học: "Organizing Encyclopedic Knowledge based on the Web and its Application to Question Answering" ppt
... our Web- based method (see Sections and 3), and evaluated the quality of the encyclopedia itself Second, we applied the generated encyclopedia to our QA system (see Section 4), and evaluated its ... question, random choice can be performed to improve the coverage to 100% Thus, for each knowledge resource we compared cases without/with random choice, which are denoted “w/o Random” and “w/ Random” ... respectively Table 1: Coverage and accuracy (%) for different question answering methods Resource Nichigai Web Nichigai + Web w/o Random C A 50.0 65.0 92.5 48.6 95.0 63.2 w/ Random C A 100 45.0 100 46.9...
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Chapter 1 Introduction to Routing and Packet ForwardingRouting Protocols and Concepts quangkien@gmail.com.Topicsl Inside the Router Ÿ Routers are computers Ÿ Router CPU and Memory Ÿ Internetwork Operating System Ÿ Router Bootup Process Ÿ Router Ports doc
... CPU and Memory Ÿ Internetwork Operating System Ÿ Router Bootup Process Ÿ Router Ports and Interfaces Ÿ Routers and the Network Layer Path Determination and Switching Function Ÿ Packet Fields and ... Router CPU and Memory l Internetwork Operating System l Router Bootup Process l Router Ports and Interfaces l Routers and the Network Layer Routers are Computers Leonard Kleinrock and the first ... commands in startup-config file (NVRAM) If boot system commands in startup-config a Run boot system commands in order they appear in startup-config to locate the IOS b If boot system commands...
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Báo cáo y học: " Mechanism of HIV-1 Tat RNA translation and its activation by the Tat protein" ppsx
... sense strand (see the colour codes) With this first PCR, the exon1 sense strand partially hybridizes with the exon2 antisense strand and the exon1 antisense strand with the exon2 sense strand Then ... (Table and Additional file 1) and the Vent polymerase (New England Biolabs, Ipswich, MA, USA) Then, reconstitution of the Tat1 and Tat2 DNA fragments was carried out (Fig 1B): minus strand ODNs ... inhibitors, and RNasin (40 U/ml)), and cells were lysed by passing through a needle The cellular lysate was centrifuged at 14000 g for 10 and the supernatant was analysed for its total protein content and...
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THE MECHANISM OF PPARN3 MEDIATED DOWN REGULATION OF SODIUM HYDROGEN EXCHANGER 1 (NHE1) GENE EPXRESSION AND ITS INHIBITION BY ESTROGEN RECEPTOR n1 1
... PPARs 1.1.5 Ligands and physiological functions of PPARα and PPARδ 1.1.6 Ligands of PPARγ 1.1.7 PPARγ and adipogenesis 10 1.1.8 PPARγ and insulin sensitization ... NHE1 and cell volume 34 1.3.4 NHE1 and cell proliferation and differentiation 34 1.3.5 NHE1 and cell migration 35 1.3.6 NHE1 and heart disease 35 1.3.7 NHE1 and ... glycerolipids and cholesterol (Wanders and Tager, 1998; Bjornsson and Olsson, 2006) They are also reported to function in detoxification of hydrogen peroxide, process of transaminations, purine and polyamine...
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THE MECHANISM OF PPARN3 MEDIATED DOWN REGULATION OF SODIUM HYDROGEN EXCHANGER 1 (NHE1) GENE EPXRESSION AND ITS INHIBITION BY ESTROGEN RECEPTOR n1 2
... MDA-MB-231 and T47D were selected to be exposed to various PPARγ ligands at different doses The three cell lines express different levels of endogenous PPARγ receptor (Figure 2D) Prostaglandin J2 and its ... ligands on NHE1 protein is not drug specific, but is conserved in both the endogenous and synthetic PPARγ ligands.The difference in extent of NHE1 repression by 15d-PGJ2 and synthetic PPARγ ligands ... synthetic PPARγ ligands which are clinically available for treatment of type diabetes Members of TZDs include troglitazone, rosiglitazone, and pioglitazone, marketed as Rezulin, Avandia and Actos respectively...
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THE MECHANISM OF PPARN3 MEDIATED DOWN REGULATION OF SODIUM HYDROGEN EXCHANGER 1 (NHE1) GENE EPXRESSION AND ITS INHIBITION BY ESTROGEN RECEPTOR n1 4
... PPARγ activation leads to down-regulation of NHE1 expression, and PPARγ ligands significantly inhibited the short-term cell viability and long-term colony forming ability in various breast cancer ... formation and loss in colony-forming ability brought about by 15d-PGJ2, we concluded that repression of NHE1 expression by PPARγ ligand is involved in the anti-tumor effects of PPARγ ligands 3B ... serum variability and ensure more consistent effect on human marrow cells (Murate et al., 1988) To test the interference of regular serum on PPARγ activation by PPARγ ligands and to select an...
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THE MECHANISM OF PPARN3 MEDIATED DOWN REGULATION OF SODIUM HYDROGEN EXCHANGER 1 (NHE1) GENE EPXRESSION AND ITS INHIBITION BY ESTROGEN RECEPTOR n1 6
... Badawi, A F and M Z Badr (2003) "Expression of cyclooxygenase-2 and peroxisome proliferator-activated receptor-gamma and levels of prostaglandin E2 and 15deoxy-delta12,14-prostaglandin J2 in ... complex and preventing the binding of activated PPARγ to its response element The data offer an explanation for the attenuated down-regulation of NHE1 expression by PPARγ ligands, and its weaker ... To this end, MCF-7, MDA-MB-231 and T47D cells were treated with different doses of synthetic ligands as well as natural ligand of PPARγ, and the protein expression and mRNA transcript level of...
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THE MECHANISM OF PPARN3 MEDIATED DOWN REGULATION OF SODIUM HYDROGEN EXCHANGER 1 (NHE1) GENE EPXRESSION AND ITS INHIBITION BY ESTROGEN RECEPTOR n1 3
... between the PPARγ receptor level and the sensitivity to PPARγ ligands in different breast cancer cell lines strongly implies a regualtory link between PPARγ activity and its anti-tumor effects To further ... ligands To further accertain that the colonogenic inhibition by 15d-PGJ2 is common in other PPARγ expressing breast cancer cell lines, MDA-MB-231 and T47D cells were also subjected to 1µM and ... MCF-7 (3 X10 cells/6-well dishes) cells were exposed to (A) 15d-PGJ2 and (B) ciglitazone for 16h before they were washed and reseeded at a density of 1.0 X104 cells/100mm dish After 14 days of...
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THE MECHANISM OF PPARN3 MEDIATED DOWN REGULATION OF SODIUM HYDROGEN EXCHANGER 1 (NHE1) GENE EPXRESSION AND ITS INHIBITION BY ESTROGEN RECEPTOR n1 5
... that the both ERα and PPARγ were active in regular serum condition, probably due to the high concentration of estrogen and prostaglandins present Upon inhibition of ERα by its antagonist, the ... dimerization and transcriptionally inactive by disabling both AF1 and AF2 domains of ERα (Fawell et al., 1990) Raloxifene acts as an estrogen antagonist in both breast and uterus (Mitlak and Cohen, ... genes responsible for its anti-cancer effects include RhoB and PTEN It was shown that E2 can reverse the up-regulation of PTEN protein and 159 mRNA expression brought by PPARγ ligand, BRL49653 in...
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Regulation of DNA (cytosine 5) methyltransferase 1 in the cell cycle and its role(s) in doxorubicin mediated micronuclei formation
... (IMR90, MCF-10A and MRC5.NT) 119 32 MCF-10A and MCF7 cells treated with 5μM Dox shows that Dox inhibits proliferation in both non-transformed and transformed cell lines 121 33 MRC5.NT and MRC5.SV40 ... transposable elements and proviral DNA, and most of these elements are found to be methylated and transcriptionally inert as heterochromatin in mammalian, plants and fungi genomes (Bestor and Tycko, 1996) ... thanks to my husband for his support and understanding throughout the years Finally, I would like to dedicate this thesis with great love to my parents and my husband, without whom none of this would...
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Báo cáo y học: "Expression of Human Globular Adiponectin-Glucagon-Like Peptide-1 Analog Fusion Protein and Its Assay of Glucose-Lowering Effect In Vivo"
... resistance, type diabetes, and cardiovascular disease Diabetes 2007; 5: 1198-209 Hu XB, Zhang YJ, Zhang HT, et al Cloning and expression of adiponectin and its globular domain, and measurement of the ... adiponectin and the C-terminus of GLP-1-A Compared with native GLP-1, the fusion protein has a modified site and larger molecular size, and may circumvent the rapid inactivation and renal clearance ... hampered by its very short plasma half-life [5, 6, 13] This is due to its rapid inactivation by dipeptidyl peptidase IV and by renal clearance [5, 6, 13] Many attempts have been made to increase its...
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Real-Time Digital Signal Processing - Chapter 7: Fast Fourier Transform and Its Applications
... the DTFT of periodic and finite-length sequences Example 7.1: If the signals fx
ng are real valued and N is an even number, we can show that X
0 and X
N=2 are real values and can be computed ... TRANSFORM AND ITS APPLICATIONS Periodicity Because of the periodicity property shown in Figure 7.1, the DFT and IDFT produce periodic results with period N Therefore the frequency and time samples ... and h(n) are real-valued N-periodic sequences, y(n) is the circular convolution of x(n) and h(n) defined as y
n x
n h
n, n 0, 1, , N À 1,
7:1:26 312 FAST FOURIER TRANSFORM AND ITS...
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A study of semantic and pragmatic features of the adjective warm and its vietnamese equivalents
... nation, and the administration and control of its internal and external affairs 3.1 RESEARCH DESIGN AND METHODOLOGY This study is intended to follow quantitative and qualitative approach and develops ... study, which describes and compares some semantic and and make a sharp noisy by rubbing its legs against its body” pragmatic features of the adjective Warm in English and Vietnamese 2.2.1.3 Meaning ... works and their Vietnamese equivalents, examines how they are used and then describes them Warm-hearted AP 3.3.3 RELIABILITY AND VALIDITY Adverb +Warm Warm and + As +Warm+ as + Noun Reliability and...
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Tài liệu Báo cáo khoa học: Inorganic pyrophosphatase in the roundworm Ascaris and its role in the development and molting process of the larval stage parasites doc
... 1-0631; Sigma) and NaF on development and molting of A suum lungstage L3 to fourth-stage larvae (L4) in vitro The lung-stage L3 were obtained from the lungs of New Zealand white rabbits days after ... [35,36,41] Detection of native AsPPase activity and inhibition by IDP and NaF of larval development and molting Native enzyme activity in L3 soluble extracts and in ES products was detected by PPase-activated ... together with its direct detection in L3 soluble extracts and in ES products (1.58 ± 0.02 lmol PiÆmin)1Æmg)1 and 0.51 ± 0.03 lmol PiÆmin)1Æmg)1 protein for PPi hydrolysis, for L3 extracts and ES products,...
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Báo cáo khoa học: Isoquinoline-1,3,4-trione and its derivatives attenuate b-amyloid-induced apoptosis of neuronal cells pdf
... isoquinoline-1,3,4-trione and its derivatives as selective, irreversible, slow-binding, pan-caspase inhibitors This compound and its derivatives protected PC12 cells and primary cortical neuronal ... caspase solutions were 90% pure, and 15% SDS ⁄ PAGE revealed they contained 20 kDa and 10 kDa subunits, which is consistent with previous reports on their autocleavage and activation Selectivity of ... caspase-3 have been reported [21–24] Isatin sulfonamide and its analogues are potent and selective inhibitors of apoptosis of chondrocytes and mouse bone marrow neutrophils in cell-based models...
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Báo cáo khoa học: Molecular and functional characterization of a novel splice variant of ANKHD1 that lacks the KH domain and its role in cell survival and apoptosis docx
... 2B that VBARP-L and VBARP-S are coded by these specific exons VBARP-L and VBARP-S code for precursor proteins of 627 and 435 amino acids and with calculated peptide masses of 69 and 49 kDa, respectively ... were constructed and used to further confirm the Vpr and VBARP interaction using in vitro and in vivo interaction studies Ten microliters of 35S-labeled in vitro translated VBARP and Vpr or Nef ... were mixed and immunoprecipitated with VBARP-, Vpr- or Nef-specific antibody and analyzed by autoradiography (Fig 1A) Results indicate that both Vpr and VBARP were able to form a complex and the...
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Chapter 1 – Introduction to Computers and C++ Programming pot
... Portable programs – 1989: ANSI standard – 1990: ANSI and ISO standard published • ANSI/ISO 9899: 1990 © 2003 Prentice Hall, Inc All rights reserved 16 1.7 History of C and C++ • History of C++ – – ... 21 1.10 Visual Basic, Visual C++ and C# • C# – Anders Hejlsberg and Scott Wiltamuth (Microsoft) – Designed specifically for NET platform – Roots in C, C++ and Java • Easy migration to NET – ... Wide Web – – – – 1990: Tim Berners-Lee (CERN) Locate and view multimedia-based documents Information instantly and conveniently accessible worldwide Possible worldwide exposure • Individuals and...
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The Chignecto Isthmus And Its First Settlers pdf
... Cumberland was in this district, and between Fort Cumberland and the old township of Cumberland, and the still older county of Cumberland, which once embraced the present Westmoreland and Albert ... premises appertaining and all the profits thereof with the right, title and interest in Law and Equity, to have and to hold the said acre of land, to him the said John Wesly and his successors in ... families, and Cumberland of thirty-five families The township of Cumberland of (sic) was given 18,800 acres of marsh, and Sackville had 1,200 cres of marsh and 8,700 acres of woodland In 1763,...
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THE AESTHETIC REVOLUTION AND ITS OUTCOMES doc
... understand the principle of its efficacy, and of its various and antithetical mutations How can the notion of ‘aesthetics’ as a specific experience lead at once to the idea of a pure world of art and ... emplotment of an and, the same knot binding together autonomy and heteronomy Understanding the ‘politics’ proper to the aesthetic regime of art means understanding the way autonomy and heteronomy ... himself and his readers in front of a specimen of ‘free appearance’, a Greek statue known as the Juno Ludovisi The statue is ‘self-contained’, and ‘dwells in itself’, as befits the traits of the...
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Tìm thêm: khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25